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What triggers restless leg syndrome? Some medications, such as selective serotonin reuptake inhibitors (SSRIs) and antidepressants may trigger RLS. These drugs affect the activity of dopamine. It is also linked to pregnancy.
What medications can cause insomnia? Medications that can cause insomnia include: Selective serotonin reuptake inhibitors (antidepressants such as Prozac and Zoloft) Dopamine agonists (includes some medications for Parkinson’s disease) Psychostimulants and amphetamines. Anticonvulsants. Cold medicines and decongestants. Steroids. Beta agonists. Theophylline.
Do SSRIs make restless legs worse? While effective for treating symptoms of depression and anxiety, patients who take serotonergic antidepressants, such as SSRIs or SNRIs, are at increased risk for new-onset or worsening RLS.
What happens if restless leg syndrome goes untreated? If left untreated, you may notice that your symptoms become more frequent and severe. Restless legs syndrome may cause you to get fewer hours of sleep each night. Many people with severe cases get less than five hours of sleep per night.
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